Essential Supplements and Peptides for Longevity: A Guide

Written by Lisa Tamati

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Posted on October 20 2025

In our ever-evolving journey toward optimizing health and extending longevity, the right supplements and peptides play a crucial role. With insights from the esteemed Dr. Elizabeth Yurth of the Boulder Longevity Institute, this guide synthesises the latest in cellular health advancements. Whether you're a health enthusiast or someone looking to enhance wellbeing, read on to discover the essentials for sustained vitality.

Core Supplements for Cellular Health

The Synergy of D3, K2, and Magnesium

For foundational health, the combination of Vitamin D3, Vitamin K2, and Magnesium is indispensable. These nutrients not only support bone health but also enhance cardiovascular function and immune defense. Ideally, aim for:

  • Vitamin D3: 5,000 to 10,000 IUs daily.
  • Vitamin K2: 1,000 IUs to ensure calcium is directed to bones, not arteries.
  • Magnesium: 500 to 1,000 mg, aiding muscle function and cardiovascular health.

Lipid Optimization: Omega-3, Fatty 15, and Plasmalogens

Lipids are vital for brain function, cell membrane integrity, and overall health. Consider incorporating:

  • Fatty 15: A breakthrough lipid derived from full-fat dairy, shown to outshine omega-3 in cellular benefits.
  • Plasmalogens: Protects neurons and supports cognitive function. Using Prodrome Neuro supplements can be beneficial.
  • Olive Oil: A tablespoon daily of high-grade extra virgin olive oil is a simple yet powerful addition for reducing inflammation and enhancing glucose regulation.

Gut Health: The Foundation of Wellbeing

A healthy gut is central to overall health:

  • Tributyrin: Supports gut lining health.
  • Lactulose: A prebiotic that facilitates healthy bacterial growth.
  • Trehalose: Aids in balancing gut flora and preventing glucose spikes.

Crucial B Vitamins

B vitamins, especially B12 (as methylcobalamin), methylfolate, and riboflavin, are essential for energy production, DNA repair, and cognitive health. Consider a high-quality B complex supplement to maintain balanced vitamin levels.

Advanced Peptide Therapy for Longevity

Key Peptides: Balancing Hormones and Repair

  • Thymosin Alpha-1: Boosts immune function, particularly useful as we age.
  • BPC-157: Aids in repair processes, particularly in gut healing.
  • Growth Hormone Secretagogues: Such as Ipamorelin or CJC-1295, promote natural growth hormone release.
  • MOTS-c: Enhances mitochondrial function, vital for energy production.

Epitalon for Pineal Gland Support

To maintain circadian rhythm and improve sleep quality, consider cycling epitalon, a peptide that supports pineal gland health.

Conclusion: Your Path to Enhanced Longevity

Pioneering your health journey with the right supplements and peptides can redefine how you age. Embrace a proactive approach today for a vibrant, long-lasting tomorrow. Whether it's boosting cellular health or advancing with cutting-edge peptides, take the steps to support your body's innate resilience. For personalized advice and advanced peptide protocols, connect with Dr. Elizabeth Hewess or explore the Boulder Longevity Institute's resources.

Remember, investing in your health yields the greatest returns. Start small, stay consistent, and foster a future brimming with vitality.

Watch the full interview with Lisa and Dr Yurth on Lisa's youtube channel here